L-Theanine

 How about nootropics L-Theanine?

L-Theanine mainly occurs in the tea plant, along with caffeine, and the nootropic

benefits of tea leaves are mainly due to this L-Theanine, it occurs in all types of

teas, black, brown. white, green, but more it occurs in matcha

It can be made synthetically in the lab but most preferred is naturally extracted

from tea leaves. On average it's present in about 1% in the dry weight of 

tea leaves,(1)

Apart from tea leaves it also reported occurring in some varieties of mushrooms

but in very low amounts

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                     nootropics, l-theanine

What is L-Theanine?

Its amino acids, mainly present in tea, and overall it affects relaxation, focus

calming, and sleep, which all are required for some nootropics. It also has a

a very unique property that it can change taste perception to a great degree, 

which means it reduces the bitterness of chocolates and grapefruit if taken

along with this. It's another great activity is that it increases the sensation of

fullness means it increases the time between two food intakes, in layman terms

it reduces hunger,(2)

let's see

                    nootropics,l-theanine

How really L-Theanine works?

Mainly it effect the brain , and some very significant developments takes place 

moment you take L-Theanine or you take tea,(3)

-it increases the levels of GABA,serotonin,dopamine, all these works as

 neurotransmitters and contributes to the regulation of

--------emotions,mood,concentration,alertness, and sleep

--------appetite, energy,other cognitive skills

-it reduces the levels of excitatory brain chemicals, it means it reduces

 those chemicals which are responsible for stress and anxiety, and by

 doing so it reduces

--------stress, anxiety

-it enhances alpha-brain waves, its also called wakeful relaxation or

 in layman terms relax without sedating effect

------- improves sleep

Overall health benefits of L-Theanine?

As you have seen in the above para it mainly works with brain, it correct and

recorrect the brain functions, so in very obvious way its best in this area and

it really does wonders,(4)

-improves the brain functions, emotions,mood,concentrations,alertness,sleep

-reduces stress and anxiety

-reduce and maintain a healthy weight

What are the doses?

-for sleep,stress,anxiety 100-mg to-400-mg

-for other user a combination with caffeine where

--------caffeine 12-to-100-mg

--------theanine 30-to-100-mg

What are the side effects of L-Theanine?

It's very well tolerated in most the cases

-pregnant and breastfeeding, don't take without informing to doctor

-low blood pressure, as it can reduce more blood pressure, so carefully

-children, only after informing to doctor

What can be interactions?

If you are on some kind of medication then better discuss with your doctor

before taking it as it may have interaction with medicines of blood pressure

stress, anxiety, sleeping pill, etc

Also careful if you are taking stimulants, and any caffeinated drinks, or energy

drinks

Does L-Theanine work as a very good nootropic?

As you see it has most of the activity in the area of the brain, and in fact, it is already

very well used in a lot number of supplements meant for nootropics, so there should

not be any doubt about its working as a great nootropics

So, where do we stand in this case of L-Theanine, from this blog,

 About Nootropics, Nootropics Facts?

As we are in the process of analyzing a number of ingredients natural and or

synthetic which have nootropic activity, this L-Theanine is one of the most 

promising one and because of its greater benefits it's used in a large number

of commercial preparations meant for nootropics, so you can try to use this

as a supplement which is available today in tablet form, we very strongly

recommend it to aged persons and also persons who are in the sports activity

MIND Diet

 What is the MIND Diet?

As the name suggests, it is the diet for the mind, and of course, its a highly dedicated diet

for the protection and health of the brain, you can say it is for controlling the decline of

brain health due to aging, It is developed by nutritional epidemiologist Martha Clare Moris

at Rush University Medical center and data is published in 2015

Its combination of two top diets Mediterranean and DASH, and in this combination all 

those foods are removed which can affect the brain,(1),(2)

MIND Diet can lower the Alzheimers risk to about 35% who follow this diet and

also reported to lower the risk about 53% who adhere to it rigorously

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                     nootropics facts, MIND Diet

The Rush research team has done follow up research studies and they concluded that it

maybe a better diet than both DASH and Mediterranean diets prevents cognitive decline

in a very significant way,(3)

One more study, that two done very recently in 2020, concluded that

MIND Diet can

-it prevents dementia

-it reduces the harmful effects due to obesity

-it increases cognitive ability

-it protects the brain structure

-it can reduce the weight, that too quick weight loss

-it boosts brainpower

-it decreases oxidative stress and inflammation

-it reduces potentially harmful beta-amyloid proteins

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                    nootropics facts, the MIND diet

What exactly is this diet?

It is around, leafy greens, nuts, and berries and planed in such a way that carbohydrates

should be present in minimum possible amounts,(4),(5)

            

What are the foods to be avoided?

-whole dairy products

    butter and margarine, less than 1-tbsp per day

    cheese, once a week only

-Red meat, not more than 3-serving per week

-pastries

-sweets

-fried foods

-Very strictly avoid  saturated and trans fats

What foods we must eat in this diet?

It recommends these foods to be taken very regularly

-Green, leafy, vegetables,

  6-serving per week, includes, kale,spinach, cooked green, and salad

-Other vegetables

 Once in a day, nonstarchy vegetables

-Berries

  twice a week, strawberries, blueberries, raspberries, and blackberries

-Nuts

  5-serving per week, vary the type and varieties

-Olive oil

 this is the oil recommended by the mind team

-Whole grains

  3-serving daily, oatmeal, quinoa, brown rice, whole-wheat pasta, whole wheat bread

-Beans

  4-times a week, all beans, lentils, soybeans

-Poultry

 2-times a week, chicken, or turkey, but not fried

-Fish

 once a week,salmon,sardines,trout,tuna,mackerel

-Wine

  not more than one glass daily, more preferred red-wine

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                    nootropics-facts, MIND Diet, what is allowed

How the diet works?

In one week of the program what you should eat,(5),(6)

-every day, you eat three servings of whole grains, salad, and another vegetable, along

  with a glass of wine

-snack on nuts

-every other day 1/2-cup of beans

-twice a weak poultry

-twice a weak 1/2-cup blueberries

-weekly once dine on fish

-oil should be olive oil

What exercises are needed?

There are not many studies on this subject, however, some exercises are better as it 

may protect the brain in the cases of higher risk for Alzheimer's disease

one study in 2014 in Frontiers in Aging Neuroscience, which recommends

-at least 2.5-hours moderate activity per week

-brisk walking

-muscle-strengthening activities

MIND Diet Examples

Breakfast

-yogurt, with raspberries with almonds

-wheat toast, scrambled eggs, almond butter

-oatmeal, strawberries, boiled eggs

-yogurt,banana,peanut butter

-wheat toast, omelet with peppers, onions, avocado

-oats overnight soaked with strawberries

-spinach frittata, apple, peanut butter

Lunch

-tuna salad,wheat bread,carrots,celery,hummus

-fish tacos, wheat bread, brown rice, pinto beans

-ground turkey

-baked trout, collard greens, black-eyed peas

-salad,black beans,grilled chicken,corn,onion

-sandwich, chicken, blackberries, carrots

-whole-wheat pita, salad, chicken

Dinner

-chicken, vegetables, brown rice

-salmon grilled, salad, brown rice

-brown rice, black beans, vegetables

-whole-wheat spaghetti,salad,meatballs

-oven-roasted potatoes, salad, wheat bread, chicken

-whole-wheat pita, salad, chicken

-brown rice chicken curry, lentils

So, from this blog, Nootropics facts, we do recommend following this MIND diet, for

persons who are aging, just to prevent the faster aging, it's very important, what very

silent key factors are we must adhere to get maximum benefits

-First point is not to use sugar at all, no surgery products

-Second point, is not to use butter, cheese, or margarine, or only use little

-Third point, no more fried products you can use grilled and roasted ones

-Forth point, no hard meat only chicken, fish, and egg

-Fifth point, no starchy vegetables only leafy

These are good points for any diet, so try to change food habits and try to adopt a very

healthy diet, which gives strength to the brain

Vinpocetine

What is Vinpocetine? 

It's a very powerful drug, also called ethyl apovincaminate, its lab-made derivative of

vincamine which is isolated from plant vinca, so you can say half natural and half synthetic

so let's go through this plant vinca from which vincamine is isolated, it is sold as its brand

name,Cavinton and Intelectol,(1),(2)

What is this vinca plant?

It's very common flowering plant, called by popular name periwinkle, and this vincamine is

extracted from seeds and leaves of this plant, and further in the lab this vincamine is converted

to this drugvinpocetine

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                    nootropics facts, vinpocetine

Where this vinpocetine is used?

People use this for a variety of purposes such as

-improving memory

-improving thinking power

-boosting energy

-weight loss

but unfortunately, there is not much clear scientific evidence to support its uses, in fact, its a very controversial drug but in spite of all this it's used in supplements meant for nootropics, that

the real surprise, the medical community is highly divided whether it has any great usefulness

let's see what they think,(3).(4)

apart from its nootropics application, this drug is also promoted for the following health

 conditions again here also we don't have enough support from research data,(5),(6)

-age-related eye problem, AMD

-age-related hearing loss

-taking vinpocetine along with ginkgo improves memory

-reduces brain damage due to acute stroke

-for tinnitus,(ringing in the ears)

-for loss of bladder control,(urinary incontinence)

-Alzheimer disease

-Motion sickness

-Seizure disorder,(epilepsy)

-Menopause problems

It's status

It's used in Japan, Russia, and some European countries, but not in the US, Canada, Australia

, New Zealand but still sold as in supplements, where mostly it is used with ginkgo as a

 memory booster supplement

Where does it stand from the Nootropics Facts point of view?

Although it is used in many supplements meant for nootropics, but the problem is

that we don't have enough research data in the support of vinpocetine, at this situation

we feel very much reserved in recommending this drug for nootropics, after all, facts

should not be ignored

Nootropics and alpha-GPC

What is Alpha-GPC?

Its total exact name is L-alpha glycerylphosphorylcholine or another most used name

cholinealfoscerate,a natural choline compound, occurs in the brain, and its role is to transfer

choline across the blood-brain barrier

It also happens to be a biosynthetic precursor for acetylcholine, in lay-man terms it 

converts itself to acetylcholine,in the bioprocess which is constantly going on in

the body, more particularly in the brain.

Today its made in a lab and can be used as medicine,(1)

What is the role of Alpha-GPC?

As discussed its role is to manage, regulate choline in the brain, because of its this role

it becomes very important as nootropics, by taking it as a supplement, provides more

acetyl-choline, and intern more benefits to brain problems,(2)

,

Production of Alpha-GPC

Mostly it is made by a chemical or enzymatic process from soya phospholipids, which also

occurs in lecithin, mostly from eggs and soya

Sources of Alpha-GPC

Its look like its widespread in most of food products but only in very small amounts, 

the sources maximum rich are only just follow

Wheat bread.....................................     4,93 mg/100 gram

Oat barn.............                                   33.25mg/100 gram

Cream cheese...........                             9.26 mg/100 gram

Yogurt..........               ..............          8-to-9-mg/100 gram

Bananas.........    .............                       5,60 mg/100 gram

Mushrooms..............         .............       5.11 mg/100 gram

Cabbage...........     ........            ........    3.47 mg/100 gram

Salmon..........     .............                      5.89 mg/100 gram

Comparison with other choline analogs

What reported is that Alpha-GPC works much better in compression with

other choline analogs means it needs only 46% dose to create the same effect

what 100% dose of CDP-choline provides, so definitely it is more better

the choice for choline related treatments

Alpha-GPC affects on Obesity and Fat- and Weight-reduction

As we already discussed, not much research data is available, but whatever we have

indicates that it works, it creates LIPOLYSIS, which means creates ketones and free fatty

acids, once it is taken in, a similar condition which is created by keto-diet.

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                                  nootropics and alpha-GPC

It can affect physical performance

It is reported to increase about 14% more out-put, if it is taken about 45- minutes before

exercise

It improves the conditions of Ischemia and Stroke cases

Very significant improvements are reported in these cases, it's very important neuroprotective

in both cases

What are the other health benefits of Alpha-GPC?

There is not much research inputs about its benefits, whatever very primary research data

available indicates that it can provide some good benefits in the following areas,(3),(4)

Alzheimer disease

It is reported to work in this case, improve the symptoms in a very considerable way

Dementia

It improves the conditions, behavior, mood, and thinking areas

Improve memory

Improve thinking  process

Improve learning

What are the side effects or negative effects of alpha-GPC?

Although it's very much tolerated, still some side effects are reported and most of

them are very mild in nature, they are heartburn, headache, dizziness, and in prolonged

use skin rashes

There is not much research information available so be on the very safe side and don't use

if you are pregnant or breast-feeding

What is the status and doses of this Alpha-GPC?

Most of the time it is available on the counter, which means you don't need prescription

about doses not much clear although its also depends on a lot of other conditions may be age

and health, follow the instructions provided by the supplier, mostly safe dose is 1000mg per day

in divided doses of 500mg.

Does Alpha-CPC is a very good nootropic?

Alpha-GPC is only working, in the area of the brain, as it is controlled and regulate the choline

it can be the safest choice for nootropics, and in fact, it is already used in a large scale for

this purpose only, and also the truth is it is used in a number of supplements meant for

nootropics.

Where does it stand from a nootropics-fact point of view?

When we see a lot of drugs for nootropics, this alpha-GPC just stands out as something very

special, at least it is safest and very active for brain functions, we think it can be and should

be considered as most important choice as nootropics