L-Theanine

 How about nootropics L-Theanine?

L-Theanine mainly occurs in the tea plant, along with caffeine, and the nootropic

benefits of tea leaves are mainly due to this L-Theanine, it occurs in all types of

teas, black, brown. white, green, but more it occurs in matcha

It can be made synthetically in the lab but most preferred is naturally extracted

from tea leaves. On average it's present in about 1% in the dry weight of 

tea leaves,(1)

Apart from tea leaves it also reported occurring in some varieties of mushrooms

but in very low amounts

let's see

                     nootropics, l-theanine

What is L-Theanine?

Its amino acids, mainly present in tea, and overall it affects relaxation, focus

calming, and sleep, which all are required for some nootropics. It also has a

a very unique property that it can change taste perception to a great degree, 

which means it reduces the bitterness of chocolates and grapefruit if taken

along with this. It's another great activity is that it increases the sensation of

fullness means it increases the time between two food intakes, in layman terms

it reduces hunger,(2)

let's see

                    nootropics,l-theanine

How really L-Theanine works?

Mainly it effect the brain , and some very significant developments takes place 

moment you take L-Theanine or you take tea,(3)

-it increases the levels of GABA,serotonin,dopamine, all these works as

 neurotransmitters and contributes to the regulation of

--------emotions,mood,concentration,alertness, and sleep

--------appetite, energy,other cognitive skills

-it reduces the levels of excitatory brain chemicals, it means it reduces

 those chemicals which are responsible for stress and anxiety, and by

 doing so it reduces

--------stress, anxiety

-it enhances alpha-brain waves, its also called wakeful relaxation or

 in layman terms relax without sedating effect

------- improves sleep

Overall health benefits of L-Theanine?

As you have seen in the above para it mainly works with brain, it correct and

recorrect the brain functions, so in very obvious way its best in this area and

it really does wonders,(4)

-improves the brain functions, emotions,mood,concentrations,alertness,sleep

-reduces stress and anxiety

-reduce and maintain a healthy weight

What are the doses?

-for sleep,stress,anxiety 100-mg to-400-mg

-for other user a combination with caffeine where

--------caffeine 12-to-100-mg

--------theanine 30-to-100-mg

What are the side effects of L-Theanine?

It's very well tolerated in most the cases

-pregnant and breastfeeding, don't take without informing to doctor

-low blood pressure, as it can reduce more blood pressure, so carefully

-children, only after informing to doctor

What can be interactions?

If you are on some kind of medication then better discuss with your doctor

before taking it as it may have interaction with medicines of blood pressure

stress, anxiety, sleeping pill, etc

Also careful if you are taking stimulants, and any caffeinated drinks, or energy

drinks

Does L-Theanine work as a very good nootropic?

As you see it has most of the activity in the area of the brain, and in fact, it is already

very well used in a lot number of supplements meant for nootropics, so there should

not be any doubt about its working as a great nootropics

So, where do we stand in this case of L-Theanine, from this blog,

 About Nootropics, Nootropics Facts?

As we are in the process of analyzing a number of ingredients natural and or

synthetic which have nootropic activity, this L-Theanine is one of the most 

promising one and because of its greater benefits it's used in a large number

of commercial preparations meant for nootropics, so you can try to use this

as a supplement which is available today in tablet form, we very strongly

recommend it to aged persons and also persons who are in the sports activity

Vinpocetine

What is Vinpocetine? 

It's a very powerful drug, also called ethyl apovincaminate, its lab-made derivative of

vincamine which is isolated from plant vinca, so you can say half natural and half synthetic

so let's go through this plant vinca from which vincamine is isolated, it is sold as its brand

name,Cavinton and Intelectol,(1),(2)

What is this vinca plant?

It's very common flowering plant, called by popular name periwinkle, and this vincamine is

extracted from seeds and leaves of this plant, and further in the lab this vincamine is converted

to this drugvinpocetine

lets see

                    nootropics facts, vinpocetine

Where this vinpocetine is used?

People use this for a variety of purposes such as

-improving memory

-improving thinking power

-boosting energy

-weight loss

but unfortunately, there is not much clear scientific evidence to support its uses, in fact, its a very controversial drug but in spite of all this it's used in supplements meant for nootropics, that

the real surprise, the medical community is highly divided whether it has any great usefulness

let's see what they think,(3).(4)

apart from its nootropics application, this drug is also promoted for the following health

 conditions again here also we don't have enough support from research data,(5),(6)

-age-related eye problem, AMD

-age-related hearing loss

-taking vinpocetine along with ginkgo improves memory

-reduces brain damage due to acute stroke

-for tinnitus,(ringing in the ears)

-for loss of bladder control,(urinary incontinence)

-Alzheimer disease

-Motion sickness

-Seizure disorder,(epilepsy)

-Menopause problems

It's status

It's used in Japan, Russia, and some European countries, but not in the US, Canada, Australia

, New Zealand but still sold as in supplements, where mostly it is used with ginkgo as a

 memory booster supplement

Where does it stand from the Nootropics Facts point of view?

Although it is used in many supplements meant for nootropics, but the problem is

that we don't have enough research data in the support of vinpocetine, at this situation

we feel very much reserved in recommending this drug for nootropics, after all, facts

should not be ignored

Nootropics and alpha-GPC

What is Alpha-GPC?

Its total exact name is L-alpha glycerylphosphorylcholine or another most used name

cholinealfoscerate,a natural choline compound, occurs in the brain, and its role is to transfer

choline across the blood-brain barrier

It also happens to be a biosynthetic precursor for acetylcholine, in lay-man terms it 

converts itself to acetylcholine,in the bioprocess which is constantly going on in

the body, more particularly in the brain.

Today its made in a lab and can be used as medicine,(1)

What is the role of Alpha-GPC?

As discussed its role is to manage, regulate choline in the brain, because of its this role

it becomes very important as nootropics, by taking it as a supplement, provides more

acetyl-choline, and intern more benefits to brain problems,(2)

,

Production of Alpha-GPC

Mostly it is made by a chemical or enzymatic process from soya phospholipids, which also

occurs in lecithin, mostly from eggs and soya

Sources of Alpha-GPC

Its look like its widespread in most of food products but only in very small amounts, 

the sources maximum rich are only just follow

Wheat bread.....................................     4,93 mg/100 gram

Oat barn.............                                   33.25mg/100 gram

Cream cheese...........                             9.26 mg/100 gram

Yogurt..........               ..............          8-to-9-mg/100 gram

Bananas.........    .............                       5,60 mg/100 gram

Mushrooms..............         .............       5.11 mg/100 gram

Cabbage...........     ........            ........    3.47 mg/100 gram

Salmon..........     .............                      5.89 mg/100 gram

Comparison with other choline analogs

What reported is that Alpha-GPC works much better in compression with

other choline analogs means it needs only 46% dose to create the same effect

what 100% dose of CDP-choline provides, so definitely it is more better

the choice for choline related treatments

Alpha-GPC affects on Obesity and Fat- and Weight-reduction

As we already discussed, not much research data is available, but whatever we have

indicates that it works, it creates LIPOLYSIS, which means creates ketones and free fatty

acids, once it is taken in, a similar condition which is created by keto-diet.

lets see

                                  nootropics and alpha-GPC

It can affect physical performance

It is reported to increase about 14% more out-put, if it is taken about 45- minutes before

exercise

It improves the conditions of Ischemia and Stroke cases

Very significant improvements are reported in these cases, it's very important neuroprotective

in both cases

What are the other health benefits of Alpha-GPC?

There is not much research inputs about its benefits, whatever very primary research data

available indicates that it can provide some good benefits in the following areas,(3),(4)

Alzheimer disease

It is reported to work in this case, improve the symptoms in a very considerable way

Dementia

It improves the conditions, behavior, mood, and thinking areas

Improve memory

Improve thinking  process

Improve learning

What are the side effects or negative effects of alpha-GPC?

Although it's very much tolerated, still some side effects are reported and most of

them are very mild in nature, they are heartburn, headache, dizziness, and in prolonged

use skin rashes

There is not much research information available so be on the very safe side and don't use

if you are pregnant or breast-feeding

What is the status and doses of this Alpha-GPC?

Most of the time it is available on the counter, which means you don't need prescription

about doses not much clear although its also depends on a lot of other conditions may be age

and health, follow the instructions provided by the supplier, mostly safe dose is 1000mg per day

in divided doses of 500mg.

Does Alpha-CPC is a very good nootropic?

Alpha-GPC is only working, in the area of the brain, as it is controlled and regulate the choline

it can be the safest choice for nootropics, and in fact, it is already used in a large scale for

this purpose only, and also the truth is it is used in a number of supplements meant for

nootropics.

Where does it stand from a nootropics-fact point of view?

When we see a lot of drugs for nootropics, this alpha-GPC just stands out as something very

special, at least it is safest and very active for brain functions, we think it can be and should

be considered as most important choice as nootropics

Nootropics and glutamic acid

Glutamic acid

Glutamic acid is an amino acid used by almost all living species, it contributes as an

 important part of biosynthesis for proteins, the human body makes it for its needs,

 it involves in the functions of the nervous system, the very interesting part is that

 it occurs in protein gluten which also happens to be the major protein of wheat,

 so it's plenty around us,(1)

It is manufactured by either hydrolysis of the protein gluten, or from wastewater

 of beetroots, or by fermentation

What is the connection of glutamic acid with the brain?

This is an amino acid that is involved between nerve cells and brain cells, which means

 it involved in sending and receiving information, so its very key amino acids involved

 with brain functions,(2)

let's see

                               nootropics and glutamic acid

Does MSG, monosodium glutamate has the same acid?

Yes, its the same acid, only here it is used as the sodium salt, MSG has a lot of controversy

and some people working with the health system regard this as a little unsafe, although

the FDA says it's very safe. Its food additive also called as number E621 used very widely

as a flavor enhancer in processed foods

MSG contributes in a very big way as a flavor enhancer mainly for savory, meaty, and

 umami foods, here umami is referred to as the fifth taste along the line of salty, sour,

 bitter, and sweet today daily intake of MSG in the US and UK is about 0.55-to-0.58

 gram per day, while the same in Japan and Korea is about 1.2-to-1.7 gram per day

Why MSG regarded by some people as a little unsafe?

There is not much research support for this, of course, very large doses of MGS can raise

glutamic acid levels in the blood, which means increased glutamate activity in the brain and 

can harm, but who eats that kind of high amounts

Glutamic acid health benifites

Although not much research has been done, whatever very little information we have it is

helpful in a number of health conditions

-may be helpful in treating childhood behavioral issues

-maybe helpful in personality development, mainly to Childs

-may be helpful for the treatment of epilepsy and muscular dystrophy

-maybe helpful in managing intellectual disorders

-may be helpful in the treatment of low blood sugar,(hypoglycemia) in diabetics

-maybe in preventing nerve damage in cases of chemotherapy

Glutamic acid side effects, toxicity, and possible interactions

In practice glutamic acid is not taken as a signal item most of the time it is used

in formulations along with either other amino acids or with vitamins, and again

in the formulations pinpointing side effects is a little difficult, but again what

research says,(3)

no high dose for a long lime

no for women, pregnant or breastfeeding

no for someone who has maple syrup urine disease, or MSUD, a kind of metabolic disorder

no for cystinuria, its a kidney disorder

Why glutamic acid is important as nootropics?

There is very little research information we have about its direct role as nootropics

but as it is a very important part of the glutamine cycle which really involved in high

levels of nootropics activity, it might be thought that this acid may also be useful

in nootropics activity.

let's see

                           nootropics and glutamic acid

Is glutamic acid is used as a nootropic in formulations?

Yes, and that is the reason we are trying to cover its all facts so that it should be more 

clear, whether it should be used or not, as for as commercial information is concerned

glutamic acid is a part of formulations that are marketed as supplements meant for

nootropics

So, what is a recommendation from Nootropics Facts, as already you see it does have

indirect relation with glutamine, but whether glutamic acid also works in a very good way

is not very clear, there is not much research support on this

Nootropics and Choline

What is choline?

Very recently only in 1998, choline is recognized as an essential nutrient,  and this is made by the body for its own needs.it's required for the normal function of the body for normal health. Although the body makes but a large amount also comes from food that we take every day.It's an organic, water-soluble  compound its neither vitamin nor mineral  and often grouped along with the vitamin B complex group due to its similarities,

 it impacts on

Liver function 

Healthy brain  function 

Nerves system  function 

Metabolism  function 

Therefore adequate  amounts  are always  needed for the body to function  properly,(1),(2) 

Let's see

                                       Nootropics and choline

What choline does?

Choline plays a very important  role in many processes  going on in the body some of them are

Cell structure 

It makes the cell membrane 

Cell messaging 

It is involved in  the  production  of  compounds  that acts as cell messengers at transport and metabolism It's required  for removing the cholesterol  from the liver, if it is inadequate  then there is the buildup of cholesterol  levels 

DNA synthesis 

Choline with vitamin -B12, and Folic acid takes part and produce DNA

Nervous system  maintenance 

It's important to produce  acetylcholine which is a neurotransmitter for the nervous system 

And this is also involved  in 

Memory 

Muscle movement 

Heartbeat regulations 

Other basic functions 

How much is required? 

This also depends on  gender and age and health conditions but a healthy individual  needs about 550mg/ day

What are health benefits? 

1., May be helpful to  Heart health 

Choline may reduce the risk of heart  disease  by lowering the homocysteine levels 

2,:-May help in Brain problems 

It regulates and improves 

Memory, mood, and intelligence 

Better memory and processing

Brain development 

Mental health  disorders 

Mood disorders 

Bipolar disorder 

3,:-May help in liver disease 

It reduces  liver risk by 28%

4,:-May help in Cancer

There are mixed results  and more research is  needed

What are the negative impacts? 

Taking too much choline  can be harmful it can create  side effects  such as a drop in blood pressure, sweating, fishy body odor, diarrhea, nausea, and vomiting The upper limit is 3500mg/day, this limit is just not possible if you are not taking any choline supplements,(3),(4)

Does it good for nootropics? 

It has all properties to help Brain, and because of that it is good for nootropics and in fact is already present in many supplements meant for nootropics. 

So, where does choline stands, as for as nootropics facts are concerned choline is too important as a nootropic, about nootropics activity its basic molecule involve in brain activities, we think choline and choline derivatives can be a very interesting choice as nootropics?

Nootropics and Carnitine

What is Carnitine?

L-Carnitine is a derivative of naturally occurring amino acid, its very popular,  and used for bodybuilding, fitness, and weight loss programs as a supplement. In a broad sense, it is a nutrient and dietary supplement 

It's produced in labs and it is a synthetic product, the body itself produces it for its needs, very small amounts it can be managed from food, what we eat particularly meat and fish. For some people, vegans or people with certain  genetic  issues, it has to be given as a supplement,(1).,(2)

 Let's see 

                            Nootropics and  Carnitine

What are different types of carnitine?

The several types of carnitine which are used for supplements  are

L- Carnitine

This is the most required type and standard  bioactive form of carnitine

D-Carnitine

This is a very inactive form, it should not be used

Acetyl- Carnitine

Most active form for the brain, this is more beneficial for people with neurodegeneration.

Propionyl - L-Carnitine

More active form for blood circulation improves blood flow

L -Carnitine-L-Tartarate

More active form for supplements  meant for sports, weight loss For most people, acetyl-L-Carnitine is the best working type

How it works? 

Its main role in our body is

1,:-Energy production

2,:-Mitochondrial function

In cells carnitine transport fatty acids, where they burn and produce energy,  for this purpose, most carnitine, about 90% only contained in muscles where it produces energy by utilizing fatty acids as fuel, and in turn, it helps in weight loss.

Where it occurs in nature?

                            Carnitine  in Nature

What are the health benefits of  Carnitine? 

Carnitine is associated with energy production that too in muscles, where it utilizes fatty acids rather than carbohydrates.

1,:-May help in weight loss

It really works, research studies confirm this.

2,:-May help in exercise  performance 

These benefits  are indirect and it takes  time, these are long term benefits,(3) 

Recovery

May improve  exercise  recovery 

Muscle oxygen supply

May increase oxygen supply to muscles

Stamina 

May increase blood flow,  delay discomfort, and reduce fatigue 

Muscle Soreness

May reduce muscle  soreness after exercise 

Red blood cell  production 

May increase the production of red blood  cells, which are also responsible  for oxygen 

Transport to full body

3,:-May help brain

It provides  almost all-round  health benefits  in this area studies suggested that

It prevents age-related mental decline

It improves  markers of learning 

It protects the brain from cell damage 

4:-May help Heart

It reduces  blood pressure 

It increases blood  circulation 

5,:- May help in diabetes  type2

It reduces blood sugar levels 

It improves  your body ability  to use carbohydrates 

What are the negative impacts? 

There are no negative effects  seen  in people  taking it 3 gram/ day, some people  reported  some mild side effects  such as  nausea and  stomach discomfort 

What should be dosed?

Although  recommend doses varies from 500 to 2000 gram/day depending on for what the purpose it is  used

Who should take it?

Older adults,  vegans, and vegetarians

Some very specific  use such as for cases of brain, and blood circulation 

Does it good for nootropics? 

If you see it used for more betterment for the brain, so it should  be used as nootropics in fact, it is used in a lot of supplements  meant for nootropics 

So what we have to say about this, from nootropics facts point of view, it's most trusted drug today, about nootropics activity, it has more than enough activity in the area of brain and brain functions, its side effects are also very limited, all said and done it can be very good choice.

Nootropics and DMAE

What is  DMAE?

Actually, it is chemical, its name is dimethylethanolamine, it's bifunctional, which means it has two reactive groups, one anime other alcohol, its colorless, viscous liquid with little ammonia smellIt's totally  synthetic  means it is made in labs, not isolated from  any natural product 

DMAE bitartrate

It's bitartrate salt, is a white powder, and mostly it is used as a dietary supplement, it has37% DMAE in it DMAE is naturally  produced in the body, which means it is present in the body, it's also present in fatty fishes such as anchovies, sardines, and salmon.,(1),(2)

Let's see 

                               Nootropics and  DMAE

How it works? 

It works by increasing the production of acetylcholine, a neurotransmitter involved in sending signals to nerves. Acetylcholine is also supposed to be responsible  for regulating many functions of the brain such as,(3),(4)

Sleep

Muscle contractions

Pain responses

Also, prevent the formation of beta-amyloid buildup in the brain, beta-amyloid is responsible for the age-related decline of brain function,  such as memory  loss

What are the health benefits of DMAE? 

There are not many  research studies in this area, and also whatever  information  we have is an old one

1,:-Support memory 

Very little evidence  in this area, it may be helpful to  protect memory 

2,:-Reduce hyperactivity

In this area, it is reported to  be helpful,  particularly  in children's 

3,:-Improve moods

Research studies indicate that DMAE  helps in this area 

Reduces depression, anxiety, and irritability

Increases motivation and initiative 

Enhance  mood

4,:-Enhance athletic  performance 

It improves  athletic  performance  when given  with vitamins and other supplements but we need more  research  in this area

5,:-May help in the Skin area

It works in this area, and a small study  is there to support  this

It hydrates skin

It improves  skin appearance 

It reduces fine lines around the eyes  and on the forehead 

Reduces wrinkles  of skin

Improve the firmness of the skin

What are the negative impacts?

Should not be taken by those having epilepsy, schizophrenia, and bipolar  disorders

Don't take if you are or might pregnant

Don't take if you are breastfeeding

What is the potential risk?

If taken in high doses,  it can trigger 

Skin irritation, redness, and swelling 

Muscle twitching

Insomnia 

Sneezing, coughing, and wheezing

Eye irritation 

Convulsion, only to very rare cases

It can also trigger  potentially  dangerous  interactions to certain medication,  so must 

inform your doctor 

What are the other names of this product? 

Apart from calling it as DMAE, its also called as

Deanol

Acetamido-benzoate de deanol

Benzilate de deanol

Bisorcate de deanol

Cyclohehylpropionate deanol 

Deanol  aceglumate

Deanol hemisuccinate

Deanol  pidolate

Deanol  tartrate

Does it worth as nootropics? 

In spite of side reactions  and also not much information  available  about these products, this is also one of the most used products in supplements meant for nootropics.,(5) 

So where do we stand, from nootropics facts point of view, this product is great, its effective about nootropics activities also it works, and doctors are using it in a big way, and a lot of research studies information we have, we think it can be used as nootropics, but as it is the drug, you must inform your doctor before taking a decision about this.

Nootropics and Nicotine

About nicotine

It's tobaccos main ingredient, widely used as a stimulant, and at the same time highly addictive, and very well known for its bad effects,  so what is good about it. according to  research  carried out, where pure nicotine,  not tobacco, is tested and it found,(1),(2) ,that it can protect from

Alzheimer's disease 

Parkinson's disease 

Even ward off these diseases 

Even it reduces  the  anxiety 

Improve memory and concentration 

But because its bad effects are so high, the medical circle does not want to take the risk.

Let's see 

                                 Nootropics and Nicotine

Does it act as nootropics? 

It does have some good effects on the brain, but whether we should use it as nootropics is a question,  unanswered,  however, it is used in some supplements meant for nootropics,(3). 

So, what we have to say about this, from a nootropics facts point of view, and about nootropic activities it provides a very great picture, but again possibilities of bad happening, and addiction stop us to say that it can be a too good a choice, although it is used in supplements meant for nootropics

Nootropics and Caffeine

About Caffeine 

This is a natural ingredient of tea, coffee, and cacao plants, and also maybe the most used ingredient in the world,  most of the people start their day,  from this.It works on the brain and CNS system and provides energy,  stimulation, and alertness. Its history  is as old as 2737 BC, with the discovery of  tea now, today its also main ingredient of  caffeinated soft drinks and also in almost all energy drinks,(1).,(2)

Let's see 

                        Nootropics and  Caffeine

How it works? 

Most of the caffeine is taken orally,  and is absorbed, and goes to the main bloodstream very fast, from there it reaches the liver where it breaks down to smaller compounds which further, go to almost all parts of the body's main function is in the brain, where it blocks the effect of adenosine. Adenosine acts as a neurotransmitter and what it does is, make the brain  slow down, or relax, in the end, this translate to  tiredness, so caffeine  overcome the effects  of tiredness, make fresh good mood and feel fresh In the process of overcoming the adenosine effect, caffeine  goes the other way and keeps you alert, stay awake, also increases the levels of adrenaline which  increases brain activity by more release of,(3),(4)

Dopamine

Norepinephrine

These both are very important neurotransmitters, keep the brain very active.

How fast caffeine works?

Caffeine  works very fast, the moment you drink coffee,  it takes only less than  20 minutes for caffeine  to reach the bloodstream, and almost about one hour to create the full effect 

What are the health benefits of  Caffeine?

1,:-Improve the brain function 

It affects the brain in a big way and that too in speed

Good mood, or mood elevation

Improved alertness

Improve reaction time

Help in Alzheimer's disease 

Help in Parkinson's disease 

2,:-Increase metabolism 

As it stimulates CNS, it increases metabolism by 11% and this results in fat burning which also get the increases by 13%, in nutshell, it means that if you take 300 mg of caffeine it can burn about  79 calories. 

3,:-May enhance exercise performance 

It delays muscles reaching exhaustion

It improves  muscle contractions

It increases tolerance to fatigue 

It reduces  perceived exertion

It helps in team sports,

It helps in high intense workout 

It helps in resistance  exercise 

4,:-May be helpful  in Heart health 

Caffeine does not raise heart risk, actually it is the other way around it lowers heart risk about 16 to 18% for men and women who are drinking  1 to 4 cup of coffee per day, more precisely about 100 to 400 mg caffeine per day. It can raise blood pressure in a very small margin about 3 to 4 mm, hg only, and also attend to fade after some time.

5,:-May help in diabetes 

It lowers about 29% risk of developing diabetes type-2

6,:-May protect the liver

It reduces  the risk  of liver damage  by as much as 84%It may slow disease progress It improves treatment  response It lowers the risk of death  because of  liver problems 

7,:-May help in Cancer

Drinking  2 to 3 cup of coffee  may reduce cancer risk

Liver cancer by 64%

Colorectal cancer by 38%

Skin cancer by 20%

8,:- May help gut health 

It may increase activities  of gut-friendly  bacterias,  and it kills bad bacterias 

9,:- May help in Gout

It may reduce the risk of  developing  gout 

In men about 40%

In women  about  57%

10,:- Reduces multiple sclerosis, (a chronic illness  involving  CNS )

It reduces  the  symptoms, in this disease, also reduces  the risk of developing  this disease  by 30%

11,:-Longevity

Drinking  coffee  may decrease  the risk of death by 30% in cases of diabetes 

What is the negative impact? 

Most importantly it is habit-forming some side effects are anxiety, tremors, restlessness, irregular heartbeat, trouble sleeping. It can increase headache and  migraine and high blood pressure  in some individuals It can also increase the risk of  miscarriage There is the possibility  that it can react with  medication  if you are taking  and avoid caffeine  if you are taking 

Zanaflex, a muscle relaxant

Luvox, a antidepressant

What is recommended dosages of caffeine? 

From USDA and EFSA, the recommendations are only up to 400mg/ day, in terms of coffee it is 4 cups of coffee.

Does caffeine fit as good nootropics? 

Well, most of its activities are in the area of the brain, it's very affordable and manageable, and already it is used in many supplements meant for nootropics. 

So as for as caffeine is concerned, from a nootropics facts point of view it's just great it works that too works very fast, about nootropics no one should have any doubt as most of the people any way using it in the form of tea or coffee, it can be a very interesting choice, the only thing it may be addicting

Nootropics drugs

What are very important nootropics drugs?

These are synthetic  materials,  mostly they are made in labs., their status  just like most of the other drugs, that we are giving here a list which is maximumly used.,(1),(2),(3)

1,:-Caffeine

2,:-Nicotine

3,:-DMAE, and DMAE bi tartarate

4,:-Carnitine, Acetyl-L-Carnitine,L-Carnitine tartarate

Let's see

                                        Nootropics  drugs

5,:-Choline

6,:-Glutamic acid

7,:-Alpha-GPC

8,:-Vinpocetine

9,:-L-Theanine

10,:-Omega-3-acids

Let's see 

                                        Nootropics  Drugs

11,:-Phosphatidyl serine

12,:-Vitamin-B1, B6, B12

13,:-Noopept

14,:-Piracetam

15,:-Phenotropil

16,:-Modafinil

17,:-Adderall, ( amphetamine)

18,:-Ritalin, (Methylphenidate)

19,:-Citicoline

Let's see 

                                     Nootropics  drugs

There are many others but these are the most used ones, these are drugs, and for some prescription may be necessary from a doctor.

Nootropics facts are that in almost all supplements meant for nootropics contains either one or a mixture of more than one of these drugs, more often they are used along with natural nootropics, about nootropics functions these are very well established in the market of nootropics.

Most of them are lab-made, or in other terms made by chemical synthesis, some of them also present in natural products, like caffeine but as a thumb rule they all are made in labs, not isolated from natural