MIND Diet

 What is the MIND Diet?

As the name suggests, it is the diet for the mind, and of course, its a highly dedicated diet
for the protection and health of the brain, you can say it is for controlling the decline of
brain health due to aging, It is developed by nutritional epidemiologist Martha Clare Moris
at Rush University Medical center and data is published in 2015

Its combination of two top diets Mediterranean and DASH, and in this combination all 
those foods are removed which can affect the brain,(1),(2)

MIND Diet can lower the Alzheimers risk to about 35% who follow this diet and
also reported to lower the risk about 53% who adhere to it rigorously
let's see


nootropics-facts,mind-diet
                     nootropics facts, MIND Diet


The Rush research team has done follow up research studies and they concluded that it
maybe a better diet than both DASH and Mediterranean diets prevents cognitive decline
in a very significant way,(3)

One more study, that two done very recently in 2020, concluded that
MIND Diet can

-it prevents dementia
-it reduces the harmful effects due to obesity
-it increases cognitive ability
-it protects the brain structure
-it can reduce the weight, that too quick weight loss
-it boosts brainpower
-it decreases oxidative stress and inflammation
-it reduces potentially harmful beta-amyloid proteins
let's see


nootropics-facts,MIND-diet
                    nootropics facts, the MIND diet

What exactly is this diet?

It is around, leafy greens, nuts, and berries and planed in such a way that carbohydrates
should be present in minimum possible amounts,(4),(5)
            
What are the foods to be avoided?

-whole dairy products
    butter and margarine, less than 1-tbsp per day
    cheese, once a week only
-Red meat, not more than 3-serving per week
-pastries
-sweets
-fried foods
-Very strictly avoid  saturated and trans fats

What foods we must eat in this diet?

It recommends these foods to be taken very regularly

-Green, leafy, vegetables,
  6-serving per week, includes, kale,spinach, cooked green, and salad
-Other vegetables
 Once in a day, nonstarchy vegetables
-Berries
  twice a week, strawberries, blueberries, raspberries, and blackberries
-Nuts
  5-serving per week, vary the type and varieties
-Olive oil
 this is the oil recommended by the mind team
-Whole grains
  3-serving daily, oatmeal, quinoa, brown rice, whole-wheat pasta, whole wheat bread
-Beans
  4-times a week, all beans, lentils, soybeans
-Poultry
 2-times a week, chicken, or turkey, but not fried
-Fish
 once a week,salmon,sardines,trout,tuna,mackerel
-Wine
  not more than one glass daily, more preferred red-wine
let's see

nootropics-facts,mind-diet
                    nootropics-facts, MIND Diet, what is allowed

How the diet works?

In one week of the program what you should eat,(5),(6)

-every day, you eat three servings of whole grains, salad, and another vegetable, along
  with a glass of wine
-snack on nuts
-every other day 1/2-cup of beans
-twice a weak poultry
-twice a weak 1/2-cup blueberries
-weekly once dine on fish
-oil should be olive oil

What exercises are needed?

There are not many studies on this subject, however, some exercises are better as it 
may protect the brain in the cases of higher risk for Alzheimer's disease

one study in 2014 in Frontiers in Aging Neuroscience, which recommends

-at least 2.5-hours moderate activity per week
-brisk walking
-muscle-strengthening activities

MIND Diet Examples

Breakfast

-yogurt, with raspberries with almonds
-wheat toast, scrambled eggs, almond butter
-oatmeal, strawberries, boiled eggs
-yogurt,banana,peanut butter
-wheat toast, omelet with peppers, onions, avocado
-oats overnight soaked with strawberries
-spinach frittata, apple, peanut butter

Lunch

-tuna salad,wheat bread,carrots,celery,hummus
-fish tacos, wheat bread, brown rice, pinto beans
-ground turkey
-baked trout, collard greens, black-eyed peas
-salad,black beans,grilled chicken,corn,onion
-sandwich, chicken, blackberries, carrots
-whole-wheat pita, salad, chicken

Dinner

-chicken, vegetables, brown rice
-salmon grilled, salad, brown rice
-brown rice, black beans, vegetables
-whole-wheat spaghetti,salad,meatballs
-oven-roasted potatoes, salad, wheat bread, chicken
-whole-wheat pita, salad, chicken
-brown rice chicken curry, lentils


So, from this blog, Nootropics facts, we do recommend following this MIND diet, for
persons who are aging, just to prevent the faster aging, it's very important, what very
silent key factors are we must adhere to get maximum benefits

-First point is not to use sugar at all, no surgery products
-Second point, is not to use butter, cheese, or margarine, or only use little
-Third point, no more fried products you can use grilled and roasted ones
-Forth point, no hard meat only chicken, fish, and egg
-Fifth point, no starchy vegetables only leafy

These are good points for any diet, so try to change food habits and try to adopt a very
healthy diet, which gives strength to the brain




Vinpocetine

What is Vinpocetine? 

It's a very powerful drug, also called ethyl apovincaminate, its lab-made derivative of
vincamine which is isolated from plant vinca, so you can say half natural and half synthetic
so let's go through this plant vinca from which vincamine is isolated, it is sold as its brand
name,Cavinton and Intelectol,(1),(2)

What is this vinca plant?

It's very common flowering plant, called by popular name periwinkle, and this vincamine is
extracted from seeds and leaves of this plant, and further in the lab this vincamine is converted
to this drugvinpocetine
lets see
nootropics-facts,vinpocetine
                    nootropics facts, vinpocetine

Where this vinpocetine is used?

People use this for a variety of purposes such as

-improving memory
-improving thinking power
-boosting energy
-weight loss

but unfortunately, there is not much clear scientific evidence to support its uses, in fact, its a very controversial drug but in spite of all this it's used in supplements meant for nootropics, that
the real surprise, the medical community is highly divided whether it has any great usefulness
let's see what they think,(3).(4)

apart from its nootropics application, this drug is also promoted for the following health
 conditions again here also we don't have enough support from research data,(5),(6)

-age-related eye problem, AMD
-age-related hearing loss
-taking vinpocetine along with ginkgo improves memory
-reduces brain damage due to acute stroke
-for tinnitus,(ringing in the ears)
-for loss of bladder control,(urinary incontinence)
-Alzheimer disease
-Motion sickness
-Seizure disorder,(epilepsy)
-Menopause problems

It's status

It's used in Japan, Russia, and some European countries, but not in the US, Canada, Australia
, New Zealand but still sold as in supplements, where mostly it is used with ginkgo as a
 memory booster supplement


Where does it stand from the Nootropics Facts point of view?

Although it is used in many supplements meant for nootropics, but the problem is
that we don't have enough research data in the support of vinpocetine, at this situation
we feel very much reserved in recommending this drug for nootropics, after all, facts
should not be ignored






Nootropics and alpha-GPC

What is Alpha-GPC?

Its total exact name is L-alpha glycerylphosphorylcholine or another most used name
cholinealfoscerate,a natural choline compound, occurs in the brain, and its role is to transfer
choline across the blood-brain barrier
It also happens to be a biosynthetic precursor for acetylcholine, in lay-man terms it 
converts itself to acetylcholine,in the bioprocess which is constantly going on in
the body, more particularly in the brain.
Today its made in a lab and can be used as medicine,(1)

What is the role of Alpha-GPC?

As discussed its role is to manage, regulate choline in the brain, because of its this role
it becomes very important as nootropics, by taking it as a supplement, provides more
acetyl-choline, and intern more benefits to brain problems,(2)
,

Production of Alpha-GPC

Mostly it is made by a chemical or enzymatic process from soya phospholipids, which also
occurs in lecithin, mostly from eggs and soya

Sources of Alpha-GPC

Its look like its widespread in most of food products but only in very small amounts, 
the sources maximum rich are only just follow

Wheat bread.....................................     4,93 mg/100 gram
Oat barn.............                                   33.25mg/100 gram
Cream cheese...........                             9.26 mg/100 gram
Yogurt..........               ..............          8-to-9-mg/100 gram
Bananas.........    .............                       5,60 mg/100 gram
Mushrooms..............         .............       5.11 mg/100 gram
Cabbage...........     ........            ........    3.47 mg/100 gram
Salmon..........     .............                      5.89 mg/100 gram

Comparison with other choline analogs

What reported is that Alpha-GPC works much better in compression with
other choline analogs means it needs only 46% dose to create the same effect
what 100% dose of CDP-choline provides, so definitely it is more better
the choice for choline related treatments

Alpha-GPC affects on Obesity and Fat- and Weight-reduction

As we already discussed, not much research data is available, but whatever we have
indicates that it works, it creates LIPOLYSIS, which means creates ketones and free fatty
acids, once it is taken in, a similar condition which is created by keto-diet.
lets see
nootropics-facts,alpha-GPC
                                  nootropics and alpha-GPC

It can affect physical performance

It is reported to increase about 14% more out-put, if it is taken about 45- minutes before
exercise

It improves the conditions of Ischemia and Stroke cases

Very significant improvements are reported in these cases, it's very important neuroprotective
in both cases

What are the other health benefits of Alpha-GPC?

There is not much research inputs about its benefits, whatever very primary research data
available indicates that it can provide some good benefits in the following areas,(3),(4)

Alzheimer disease

It is reported to work in this case, improve the symptoms in a very considerable way

Dementia

It improves the conditions, behavior, mood, and thinking areas

Improve memory

Improve thinking  process

Improve learning

What are the side effects or negative effects of alpha-GPC?

Although it's very much tolerated, still some side effects are reported and most of
them are very mild in nature, they are heartburn, headache, dizziness, and in prolonged
use skin rashes
There is not much research information available so be on the very safe side and don't use
if you are pregnant or breast-feeding

What is the status and doses of this Alpha-GPC?

Most of the time it is available on the counter, which means you don't need prescription
about doses not much clear although its also depends on a lot of other conditions may be age
and health, follow the instructions provided by the supplier, mostly safe dose is 1000mg per day
in divided doses of 500mg.

Does Alpha-CPC is a very good nootropic?

Alpha-GPC is only working, in the area of the brain, as it is controlled and regulate the choline
it can be the safest choice for nootropics, and in fact, it is already used in a large scale for
this purpose only, and also the truth is it is used in a number of supplements meant for
nootropics.

Where does it stand from a nootropics-fact point of view?

When we see a lot of drugs for nootropics, this alpha-GPC just stands out as something very
special, at least it is safest and very active for brain functions, we think it can be and should
be considered as most important choice as nootropics







Nootropics and glutamic acid

Glutamic acid

Glutamic acid is an amino acid used by almost all living species, it contributes as an
 important part of biosynthesis for proteins, the human body makes it for its needs,
 it involves in the functions of the nervous system, the very interesting part is that
 it occurs in protein gluten which also happens to be the major protein of wheat,
 so it's plenty around us,(1)

It is manufactured by either hydrolysis of the protein gluten, or from wastewater
 of beetroots, or by fermentation

What is the connection of glutamic acid with the brain?

This is an amino acid that is involved between nerve cells and brain cells, which means
 it involved in sending and receiving information, so its very key amino acids involved
 with brain functions,(2)

let's see
nootropics-facts,glutamic-acid
                               nootropics and glutamic acid

Does MSG, monosodium glutamate has the same acid?


Yes, its the same acid, only here it is used as the sodium salt, MSG has a lot of controversy
and some people working with the health system regard this as a little unsafe, although
the FDA says it's very safe. Its food additive also called as number E621 used very widely
as a flavor enhancer in processed foods
MSG contributes in a very big way as a flavor enhancer mainly for savory, meaty, and
 umami foods, here umami is referred to as the fifth taste along the line of salty, sour,
 bitter, and sweet today daily intake of MSG in the US and UK is about 0.55-to-0.58
 gram per day, while the same in Japan and Korea is about 1.2-to-1.7 gram per day

Why MSG regarded by some people as a little unsafe?

There is not much research support for this, of course, very large doses of MGS can raise
glutamic acid levels in the blood, which means increased glutamate activity in the brain and 
can harm, but who eats that kind of high amounts

Glutamic acid health benifites

Although not much research has been done, whatever very little information we have it is
helpful in a number of health conditions

-may be helpful in treating childhood behavioral issues
-maybe helpful in personality development, mainly to Childs
-may be helpful for the treatment of epilepsy and muscular dystrophy
-maybe helpful in managing intellectual disorders
-may be helpful in the treatment of low blood sugar,(hypoglycemia) in diabetics
-maybe in preventing nerve damage in cases of chemotherapy

Glutamic acid side effects, toxicity, and possible interactions

In practice glutamic acid is not taken as a signal item most of the time it is used
in formulations along with either other amino acids or with vitamins, and again
in the formulations pinpointing side effects is a little difficult, but again what

research says,(3)

no high dose for a long lime
no for women, pregnant or breastfeeding
no for someone who has maple syrup urine disease, or MSUD, a kind of metabolic disorder
no for cystinuria, its a kidney disorder

Why glutamic acid is important as nootropics?

There is very little research information we have about its direct role as nootropics
but as it is a very important part of the glutamine cycle which really involved in high
levels of nootropics activity, it might be thought that this acid may also be useful
in nootropics activity.

let's see
nootropics-facts,glutamic-acid
                           nootropics and glutamic acid


Is glutamic acid is used as a nootropic in formulations?

Yes, and that is the reason we are trying to cover its all facts so that it should be more 
clear, whether it should be used or not, as for as commercial information is concerned
glutamic acid is a part of formulations that are marketed as supplements meant for
nootropics

So, what is a recommendation from Nootropics Facts, as already you see it does have
indirect relation with glutamine, but whether glutamic acid also works in a very good way
is not very clear, there is not much research support on this